佰乐博生物代理AntibodySystem，InVivoMAb Anti-Mouse CD274/PD-L1/B7-H1 Antibody (10F.9G2)体内中和抗体，活性抗体

佰乐博生物代理AntibodySystem，InVivoMAb Anti-Mouse CD274/PD-L1/B7-H1 Antibody (10F.9G2)体内中和抗体，活性抗体

名称：InVivoMAb Anti-Mouse CD274/PD-L1/B7-H1 Antibody (10F.9G2)体内中和抗体，活性抗体

别名：Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, CD274, Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1

货号：VMJ70102

宿主：Rat

适用物种：Mouse

存储缓冲区：0.01M PBS, pH 7.4.

形式：Liquid

纯度：>95%

克隆：Monoclonal

同型：IgG2b

应用：FCM, Neutralization

内毒素水平：Please contact with the lab for this information.

UniProt：Q9EP73

用途范围：仅用于科研

储存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

 

参考文献：

CD274 (PD-L1) negatively regulates M1 macrophage polarization in ALI/ARDS. PMID: 38440722

CD274 (PD-L1) Methylation is an Independent Predictor for Bladder Cancer Patients' Survival. PMID: 35020560

PD-L1 degradation pathway and immunotherapy for cancer. PMID: 33159034

USP22 Deubiquitinates CD274 to Suppress Anticancer Immunity. PMID: 31399419

Mevalonate improves anti-PD-1/PD-L1 efficacy by stabilizing CD274 mRNA. PMID: 37425040

PD-L1 (CD274) promoter hypomethylation predicts immunotherapy response in metastatic urothelial carcinoma. PMID: 37868689

Tumor Mutational Burden and Response Rate to PD-1 Inhibition. PMID: 29262275

Characterizing the tumor microenvironment of metastatic ovarian cancer by single-cell transcriptomics. PMID: 34038734

CD274 promotes cell cycle entry of leukemia-initiating cells through JNK/Cyclin D2 signaling. PMID: 27855694

PD-L1 Distribution and Perspective for Cancer Immunotherapy-Blockade, Knockdown, or Inhibition. PMID: 31507611

PD-L1 expression in human cancers and its association with clinical outcomes. PMID: 27574444

PD-L1 immunohistochemistry: Clones, cutoffs, and controversies. PMID: 35332576

PD-L1-specific T cells. PMID: 26724936

PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells. PMID: 35078921

PD-L1-PD-1 Pathway in the Pathophysiology of Multiple Myeloma. PMID: 32290052

B7-H1 pathway and its role in the evasion of tumor immunity. PMID: 12721664

B7-H1/PD-1 blockade therapy in urological malignancies: current status and future prospects. PMID: 26045125

The Updated Status and Future Direction of Immunotherapy Targeting B7-H1/PD-1 in Osteosarcoma. PMID: 33536783

Immunoregulatory molecule B7-H1 (CD274) contributes to skin carcinogenesis. PMID: 21730022

Therapeutic targeting of B7-H1 in breast cancer. PMID: 21870995

Mechanisms Controlling PD-L1 Expression in Cancer. PMID: 31668929

Immunology of B7-H1 and its roles in human diseases. PMID: 14686489