佰乐博生物代理AntibodySystem，Anti-Mouse CD279/PDCD1/PD1 Antibody (29F.1A12)体内中和抗体，活性抗体

名称：Anti-Mouse CD279/PDCD1/PD1 Antibody (29F.1A12)体内中和抗体，活性抗体

别名：Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279

货号：FMH02220

宿主：Rat

适用物种：Mouse

存储缓冲区：0.01M PBS, pH 7.4, 0.09% Sodium azide.

形式：Liquid

纯度：>95%

克隆：Monoclonal

同型：IgG2a, kappa

应用：FCM, IF, IHC, Neutralization, WB

内毒素水平：Please contact with the lab for this information.

UniProt：Q02242

用途范围：仅用于科研

储存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

 

参考文献：

CD279 mediates the homeostasis and survival of regulatory T cells by enhancing T cell and macrophage interactions. PMID: 32324337

Utility of CD279/PD-1 immunohistochemistry in the evaluation of benign and neoplastic T-cell-rich bone marrow infiltrates. PMID: 24926091

PD-1 Blockers. PMID: 26317459

Editorial: Immune Checkpoint Molecules and Cancer Immunotherapy. PMID: 30568661

Expression of PD-1 (CD279) and FoxP3 in diffuse large B-cell lymphoma. PMID: 25011996

[Artesunate upregulates the expression of CD39, CD279 and granzyme B in CD4(+) and CD8(+) T lymphocytes of patients with lung cancer]. PMID: 35583064

PD1 (CD279) and PD-L1 (CD274, B7H1) expression in primary central nervous system lymphomas (PCNSL). PMID: 24359606

Different Induction of PD-L1 (CD274) and PD-1 (CD279) Expression in THP-1-Differentiated Types 1 and 2 Macrophages. PMID: 34675601

Effects of Tussilago farfara L. Polysaccharides on the Expression of PD-1 (CD279) and PD-L1 (CD274) in Peripheral Blood and Tumor Tissue Lymphocytes in Mice with Lewis Lung Carcinoma. PMID: 32749562

Cancer cell-intrinsic PD-1: Its role in malignant progression and immunotherapy. PMID: 37716115

[Next generation of anti-immune checkpoints antibodies]. PMID: 31903901

The sorafenib anti-relapse effect after alloHSCT is associated with heightened alloreactivity and accumulation of CD8+PD-1+ (CD279+) lymphocytes in marrow. PMID: 29304116

CoViD-19 Immunopathology and Immunotherapy. PMID: 32308263

Expression patterns of the immunosuppressive proteins PD-1/CD279 and PD-L1/CD274 at different stages of cutaneous T-cell lymphoma/mycosis fungoides. PMID: 22094231

Peptide Blocking CTLA-4 and B7-1 Interaction. PMID: 33419027

PDCD1 and PDCD1LG1 polymorphisms affect the susceptibility to multiple myeloma. PMID: 31620907

The association between polymorphisms in the PDCD1 gene and the risk of cancer: A PRISMA-compliant meta-analysis. PMID: 27749524

A PDCD1 Role in the Genetic Predisposition to NAFLD-HCC? PMID: 33808740

PDCD1 and IFNL4 genetic variants and risk of developing hepatitis C virus-related diseases. PMID: 32937024

Epigenetic and Genetic Regulation of PDCD1 Gene in Cancer Immunology. PMID: 30178256

Identification of Pathogenic Immune Cell Subsets Associated With Checkpoint Inhibitor-Induced Myocarditis. PMID: 35762356

Tumor Mutational Burden and Response Rate to PD-1 Inhibition. PMID: 29262275

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. PMID: 1396582

PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior. PMID: 37348508

Identification of PDCD1 as a potential biomarker in acute rejection after kidney transplantation via comprehensive bioinformatic analysis. PMID: 36776400

CBX4 promotes antitumor immunity by suppressing Pdcd1 expression in T cells. PMID: 37691307

PD1 signal transduction pathways in T cells. PMID: 28881701

Circulating extracellular vesicles expressing PD1 and PD-L1 predict response and mediate resistance to checkpoint inhibitors immunotherapy in metastatic melanoma. PMID: 35042524

Biomarkers for Predicting Efficacies of Anti-PD1 Antibodies. PMID: 31417907

PD-1/PD-L1 Checkpoint Inhibitors in Tumor Immunotherapy. PMID: 34539412

Revisiting the PD-1 pathway. PMID: 32948597

PD1 Blockade in Cancer: Impact on Myeloid Cells. PMID: 32459997

Understanding the role of PD-L1/PD1 pathway blockade and autophagy in cancer therapy. PMID: 28367063

PD1 is transcriptionally regulated by LEF1 in mature T cells. PMID: 37523793

Emerging concepts in PD-1 checkpoint biology. PMID: 34006473

A Comparison of Murine PD-1 and PD-L1 Monoclonal Antibodies. PMID: 35925787

Distinct antibody clones detect PD-1 checkpoint expression and block PD-L1 interactions on live murine melanoma cells. PMID: 35864188

Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vaccines (B-Vaxx) in a syngeneic mouse model. PMID: 33117602