Recombinant Human NINJ1 Protein, N-GST & C-His (YHN29901)蛋白抗体

Recombinant Human NINJ1 Protein, N-GST & C-His (YHN29901)蛋白抗体

 

一、中文名称：

Recombinant Human NINJ1 Protein, N-GST & C-His (YHN29901)，NINJ1-人神经损伤诱导蛋白1，精品蛋白抗体试剂盒

 

二、产品描述

Ninjurin-1，也称为NINJ1，是跨膜（TM）蛋白Ninjurin家族的成员。它在CD19（+）、CD10（+）B细胞祖细胞中表达，在B系急性淋巴细胞白血病细胞中表达水平更高。Ninjurin-1也在其他一些成人和胚胎组织中表达，主要在上皮细胞中表达。轴切后，其表达在远端神经节段周围的神经元和雪旺细胞中上调。ninjurin-1表达上调已被确定为B系急性淋巴细胞白血病中微小残留病灶的标志物。它在体外介导同性粘附并促进背根神经节神经元的神经突延伸。已发现Ninjurin-1在肝细胞癌患者的肝组织中显示出高表达水平，这似乎与肝硬化和慢性病毒性肝炎病例有关。据报道，NINJURIN增加人肝癌细胞中p21的表达并诱导细胞衰老。

 

三、产品详情

名称：Recombinant Human NINJ1 Protein, N-GST & C-His (YHN29901)，NINJ1-人神经损伤诱导蛋白1，体内中和抗体，活性抗体

货号：YHN29901

表达系统：E. coli

种属：Homo sapiens (Human)

蛋白长度：[Asp2-Leu80] & [Gln142-Gln152]

预测分子量：38.12 kDa

性质：Recombinant

内毒素水平：Please contact with the lab for this information.

纯度：>90% as determined by SDS - PAGE.

Accession号：Q92982

应用：ELISA, Immunogen, SDS - PAGE, WB, Bioactivity testing in progress

状态：Lyophilized

保存溶液：Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

重悬：Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

运输：In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

稳定性和存储：Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名：Ninjurin - 1, Nerve injury - induced protein 1, Secreted ninjurin - 1, Soluble ninjurin - 1, NINJ1

 

四、参考文献：

NINJ1 mediates plasma membrane rupture during lytic cell death. PMID: 33472215

NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks. PMID: 38614101

NINJ1 Regulates Platelet Activation and PANoptosis in Septic Disseminated Intravascular Coagulation. PMID: 36835580

NINJ1 induces plasma membrane rupture and release of damage-associated molecular pattern molecules during ferroptosis. PMID: 38396301

NINJ1, rupturing swollen membranes for cataclysmic cell lysis. PMID: 33798414

 

详情请咨询Antibodysystem中国授权总代理-武汉佰乐博生物技术有限公司

 

武汉佰乐博生物技术有限公司作为法国Antibodysystem品牌亚洲区授权总代理。提供近3万种蛋白、抗体等核心生命科学试剂，旨在为生命科学科研工作者提供专业、全面、可靠的试剂产品。

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