Research Grade Onercept (DHB94438)

Research Grade Onercept (DHB94438)

一、中文名称：Research Grade Onercept (DHB94438)，研究级Onercept类似物

 

二、产品描述

Onercept 是一种重组的可溶性人肿瘤坏死因子-αp55 受体，可用于克罗恩病研究。

 

三、产品详情

名称：Research Grade Onercept (DHB94438)

别名：Onercept (USAN/INN), r-hTBP, R-HTBP-1, R-TBP-1, rTBP-1, TBP, TBP 1, TBP I, TNF-BP1, Tumour necrosis factor binding protein 1

货号：DHB94438

表达系统：Mammalian Cells

种属反应性：Human

同种型：Glycoprotein TNF-bp (Tumor necrosis factor-binding protein, TBP1)

克隆类型：Monoclonal

靶标：TNF, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, ICD2, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, TNFSF2, TNFA, Cachectin, ICD1

浓度：1 mg/ml

内毒素水平：Please contact with the lab for this information.

纯度：>95% as determined by SDS-PAGE.

纯化方式：Protein A/G purified from cell culture supernatant.

Accession号：P01375

克隆号：Onercept

应用：Research Grade Biosimilar

状态：Liquid

保存溶液：0.01M PBS, pH 7.4.

稳定性和存储：Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

 

四、参考文献：

Mechanism of Action of Anti-TNF Therapy in Inflammatory Bowel Disease.PMID:26896086

Clinical development of onercept, a tumor necrosis factor binding protein, in psoriasis.PMID:20718590

Onercept. Serono.PMID:14758777

Onercept for moderate-to-severe Crohn's disease: a randomized, double-blind, placebo-controlled trial.PMID:16797249

Psoriatic arthritis.PMID:15379770

New biologic therapeutics for ulcerative colitis and Crohn's disease.PMID:24502344

Population pharmacokinetics of onercept in healthy subjects.PMID:16372827

Gateways to clinical trials.PMID:12743628

Treatment of active Crohn's disease with onercept (recombinant human soluble p55 tumour necrosis factor receptor): results of a randomized, open-label, pilot study.PMID:12534402

Anti-TNF therapy in Crohn's disease.PMID:15669643

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